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Scale-up of expanded bed processes for the purification of proteins from cell homogenates

ReferenceSPC02790
Principal Investigator / Supervisor Professor Howard Chase
Co-Investigators /
Co-Supervisors
Professor Nigel Titchener-Hooker
Institution University of Cambridge
DepartmentChemical Engineering and Biotechnology
Funding typeResearch
Value (£) 144,392
StatusCompleted
TypeResearch Grant
Start date 01/01/1995
End date 01/01/1998
Duration36 months

Abstract

1. Pilot scale separations of proteins from cell homogenates using expanded beds. 2. Control and monitoring of the height and stability of the expanded bed. 3. Modelling of various aspects of expanded bed separation techniques. 4. Development of operational protocols for the control and monitoring, including optimisation, of adsorption stage and product elution strategies.

Summary

unavailable
Committee Closed Committee - Engineering & Biological Systems (EBS)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative Separation Processes Committee (SPC) [1992-1995]
Funding SchemeX – not Funded via a specific Funding Scheme
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