Award details

Increasing the efficiency of artificial insemination; improving sperm survival by oviduct components

Reference	SLP19718
Principal Investigator / Supervisor	Professor William Vincent Holt
Co-Investigators / Co-Supervisors	Professor Alireza Fazeli, Professor Paul Frederick Watson
Institution	Institute of Zoology
Department	Institute of Zoology
Funding type	Research
Value (£)	286,292
Status	Completed
Type	Research Grant
Start date	01/04/2003
End date	31/03/2007
Duration	48 months

Abstract

Although artificial insemination (AI) has been used for many years, its success rate is still limited under circumstances where sperm survival is crucial. This project aims to develop novel methods for enhancing sperm survival in vitro, basing our research on natural mechanisms by which sperm survival is promoted by the porcine oviduct. We have previously shown that a subset of proteins derived from porcine oviductal epithelial cell plasma membranes have the capacity to prolong enhanced sperm survival in vitro under capacitating conditions. In the current project we will aim to purify and characterise these proteins, confirm their ability to promote the retention of fertilising ability and synthesise them in vitro.

Summary

unavailable

Committee	Closed Committee - Agri-food (AF)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	LINK: Sustainable Livestock Production (SLP) [1996-2010]
Funding Scheme	X – not Funded via a specific Funding Scheme

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