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Atomic force microscopy characterisation of the molecular forces of adhesion in nucleic acids
Reference
SBD07530
Principal Investigator / Supervisor
Professor Saul Tendler
Co-Investigators /
Co-Supervisors
Professor Martyn Davies
,
Professor Charles Laughton
Institution
University of Nottingham
Department
Sch of Pharmacy
Funding type
Research
Value (£)
136,829
Status
Completed
Type
Research Grant
Start date
04/08/1997
End date
04/08/2000
Duration
36 months
Abstract
This cross-desciplinary application seeks to develop atomic force microscope (AFM) as a novel analytical tool for the characterisation and investigation of nucleic acids. Through the development of methods that allow single molecule forces of adhesion to be measured, the rapid quantification of single-strand-single strand and higher order interactions will be achieved on sub-milligram amounts of material.
Summary
unavailable
Committee
Closed Committee - Biomolecular Sciences (BMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
Structural biology and design applications (SBD) [1996]
Funding Scheme
X – not Funded via a specific Funding Scheme
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