Award details

Hydrolases involved in pesticide metabolism in wheat

Reference	SAP13249
Principal Investigator / Supervisor	Professor Robert Edwards
Co-Investigators / Co-Supervisors
Institution	Durham University
Department	Biological and Biomedical Sciences
Funding type	Research
Value (£)	126,204
Status	Completed
Type	Research Grant
Start date	01/06/2000
End date	01/06/2003
Duration	36 months

Abstract

In a LINK programme with Zeneca Agrochemicals, we propose to characterise and clone hydrolases active in pesticide metabolism and bioactivation in wheat and the problem weeds wild oat and black-grass, identifying key differences. As well as characterising a little studied gene family the programme will provide valuable information facilitating the design of new environmentally-friendly pesticides which can be selectively bioactivated or detoxified by hydrolysis in crops and weeds. To support these studies, Arabidopsis hydrolase mutants will be isolated by screening with herbicides which are either bioactivated or detoxified by hydrolysis. These mutants will be used to study the functioning of hydrolases in pesticide metabolism in vivo.

Summary

unavailable

Committee	Closed Committee - Agri-food (AF)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	LINK: Sustainable Arable Production SAPPIO (SAP) [1998-2010]
Funding Scheme	X – not Funded via a specific Funding Scheme

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