Award details

Do ageing processes in body systems reflect fundamental changes in cellular metabolism and molecular integrity?

ReferenceSAG09965
Principal Investigator / Supervisor Dr Andrew Collins
Co-Investigators /
Co-Supervisors
Dr Susan Duthie, Professor Lawrence Whalley
Institution University of Aberdeen
DepartmentBiochemical Sciences Division
Funding typeResearch
Value (£) 209,200
StatusCompleted
TypeResearch Grant
Start date 01/01/1999
End date 01/01/2002
Duration36 months

Abstract

Biological ageing is distinct from chronological ageing and is determined by environmental as well as genetic factors. We will examine Aberdeen Birth Cohorts from 1921 and 1936 to investigate the relationship between biological ageing in body systems and molecular biomarkers of ageing relating to oxidative stress, antioxidant status, DNA damage and repair and genomic instability. We will intensively study those subjects who show the highest and lowest rates of change in biological ageing to determine the contribution of nutritional factors on these processes.

Summary

unavailable
Committee Closed Committee - Genes & Developmental Biology (GDB)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative Initiative on Science of Ageing (SAG) [1998]
Funding SchemeX – not Funded via a specific Funding Scheme
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