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Identification of loci that encode immunoprotective antigens of Eimeria maxima through genetic linkage analyses
Reference
S20198
Principal Investigator / Supervisor
Professor Martin Shirley
Co-Investigators /
Co-Supervisors
Professor Damer Blake
,
Dr Adrian Smith
Institution
The Pirbright Institute
Department
Div of Molecular Biology Pirbright
Funding type
Research
Value (£)
257,341
Status
Completed
Type
Research Grant
Start date
22/10/2003
End date
21/10/2006
Duration
36 months
Abstract
A completely new strategy will be used to identify the loci that encode immunoprotective molecules of an antigenically complex protozoan pathogen. This work builds on the success of a 2 year BBSRC-funded pilot study and is driven by the need for sustainable, non drug-based, approaches for controlling coccidial parasites (Eimeria spp.) in chickens. Our strategy makes use of the genetics of the parasite in combination with parasite killing by the immune host. This powerful dual approach has the crucial technical strength of directing analyses towards the immunoprotective antigens and away from the far greater majority of parasite antigens that induce non-protective responses in the host.
Summary
unavailable
Committee
Closed Committee - Animal Sciences (AS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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