Award details

MUPs MHC and mate choice in house mice

Reference	S19816
Principal Investigator / Supervisor	Professor Jane Hurst
Co-Investigators / Co-Supervisors	Professor Robert Beynon, Professor William Ollier, Professor Paula Stockley
Institution	University of Liverpool
Department	Veterinary Clinical Science
Funding type	Research
Value (£)	615,242
Status	Completed
Type	Research Grant
Start date	01/05/2004
End date	30/04/2008
Duration	48 months

Abstract

This programme will define the roles of two highly polymorphic regions of the genome in the determination of mate choice among house mice: the Major Histocompatibility Complex (MHC) and the Major Urinary Proteins (MUPs). Both regions contribute to the scent signals that mediate mate choice but the molecular mechanisms of mate attractiveness have been largely unexplored. Using a combined behavioural and biochemical approach, we will explore how MHC, MUP and genome-wide heterozygosity affect the quality of male urinary signals, male attractiveness to unrelated females, and the ability of potential mates to identify scent owners. We will also determine the interplay between inherited MHC and MUP odortypes in the avoidance of inbreeding.

Summary

unavailable

Committee	Closed Committee - Animal Sciences (AS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

I accept the terms and conditions of use (opens in new window)

export PDF file

back to list new search