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Award details
Organisation and re-organisation of movements elicited by noxious stimuli
Reference
S19586
Principal Investigator / Supervisor
Dr John Harris
Co-Investigators /
Co-Supervisors
Institution
University of Nottingham
Department
Sch of Biosciences
Funding type
Research
Value (£)
259,660
Status
Completed
Type
Research Grant
Start date
01/07/2003
End date
30/04/2007
Duration
46 months
Abstract
Withdrawal reflexes, often used for the study of pain behaviour, are thought to be organised so that they directly remove limbs from the source of stimulation. This project will for the first time test this proposal directly by measuring the actual movements generated by noxious mechanical stimuli applied to different parts of the hind limb. The work will then proceed to investigate the reorganisation of, and other changes in, withdrawal reflex movements that follow the application of acute noxious stimuli to strategic positions on the limb, administration of analgesic drugs, disruption of endogenous control systems and development of chronic inflammation. The results will improve the interpretation of pain measurement in animals.
Summary
unavailable
Committee
Closed Committee - Animal Sciences (AS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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