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Neurophysiological properties of a memory trace

Reference	S18043
Principal Investigator / Supervisor	Dr Brian McCabe
Co-Investigators / Co-Supervisors	Professor Malcolm Brown, Professor Sir Gabriel Horn
Institution	University of Cambridge
Department	Zoology
Funding type	Research
Value (£)	276,608
Status	Completed
Type	Research Grant
Start date	17/07/2003
End date	16/02/2007
Duration	43 months

Abstract

Previous work showed that imprinting, achieved by exposing chicks to a visual imprinting stimulus (IS), initially leads to an increase in the proportion of neurons responding to that stimulus (IS neurons) in a memory store of the brain (IMHV). Subsequently, approximately 4h after training the proportion of IS neurons reverts to a low level, before increasing to a maximum approximately 17h later. The experiments will determine (i) whether wakefulness and sleep are involved in the depression and recovery of responsiveness to the IS and (ii) whether the IS neurons recorded after recovery has occurred are the same as, or different from the IS neurons recorded shortly after training. The experiments will elucidate fundamental aspects of information storage in the brain.

Summary

unavailable

Committee	Closed Committee - Animal Sciences (AS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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