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Calcium channel function in vasopressin cells
Reference
S16733
Principal Investigator / Supervisor
Professor Gareth Leng
Co-Investigators /
Co-Supervisors
Professor Mayank Dutia
Institution
University of Edinburgh
Department
Biomedical Sciences
Funding type
Research
Value (£)
259,900
Status
Completed
Type
Research Grant
Start date
01/05/2002
End date
01/05/2005
Duration
36 months
Abstract
Vasopressin cells, when activated, fire in a phasic pattern that is critical for the efficient secretion of hormone. This project will study the functional role of Ca2+ channels in this behaviour, and will test the hypothesis that changes in the regulation of low-voltage gated calcium channels underlie observed adaptation of pattern generation. The study will involve electrophysiological experiments in vivo and in vitro, studies of the regulation of intracellular calcium changes in isolated vasopressin cells, and studies of gene expression in identified vasopressin cells in different functional states.
Summary
unavailable
Committee
Closed Committee - Animal Sciences (AS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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