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Oocyte regulation of ovarian follicle development

Reference	S16550
Principal Investigator / Supervisor	Professor Alan Handyside
Co-Investigators / Co-Supervisors	Professor Helen Picton
Institution	University of Leeds
Department	Inst of Integrative & Comparative Biolog
Funding type	Research
Value (£)	191,788
Status	Completed
Type	Research Grant
Start date	10/06/2002
End date	10/06/2005
Duration	36 months

Abstract

An emerging concept in reproductive biology is that the oocyte plays an important role in regulating follicle development. However, this possibility has received little attention in preantral and early antral follicles, and the factors mediating this action of the oocyte are unclear. Using a mix of established and innovative molecular and cell biology approaches, this study will examine key features of oocyte regulation of granulosa cell development, primarily focussing on preantral and early antral follicles. The results will define the relationship between the ooctye and granulosa cells, with benefits for the developments of an array of new reproductive technologies and understanding of female reproductive biology.

Summary

unavailable

Committee	Closed Committee - Animal Sciences (AS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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