Award details

In vivo measurement of the synthesis rates of individual muscle proteins during wound healing

Reference	S16409
Principal Investigator / Supervisor	Professor Peter Emery
Co-Investigators / Co-Supervisors	Professor Michael Dunn, Professor Victor Preedy
Institution	King's College London
Department	Nutritional Sciences
Funding type	Research
Value (£)	201,324
Status	Completed
Type	Research Grant
Start date	01/08/2002
End date	01/08/2005
Duration	36 months

Abstract

Wound healing involves an increase in the overall rate of protein synthesis, but it is not known which proteins are affected. This project will employ a novel method to measure simultaneously synthesis rates of large numbers of individual proteins in vivo in experimental animals. The method will be used to measure synthesis rates of proteins in wounded muscle at each of the key stages of wound healing. Proteins whose synthesis has been stimulated will then be identified and characterised. The results will give a new insight into the extent to which the synthesis of different proteins is co-ordinated during rapid protein disposition and will identify key proteins whose synthesis may be modulated in situations where wound repair is compromised.

Summary

unavailable

Committee	Closed Committee - Animal Sciences (AS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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