Award details

Molecular epidemiology of Streptococcus uberis

Reference	S15848
Principal Investigator / Supervisor	Professor James Leigh
Co-Investigators / Co-Supervisors	Professor Tracey Coffey
Institution	The Pirbright Institute
Department	Div of Immunology Compton
Funding type	Research
Value (£)	167,632
Status	Completed
Type	Research Grant
Start date	01/06/2002
End date	01/06/2005
Duration	36 months

Abstract

The study aims to determine the population biology of the mastitis-causing pathogen Streptococcus uberis, using molecular data from representative samples of populations. Isolates collected in the UK will be characterised by direct nucleotide sequence determination (multilocus sequence typing) of loci encoding housekeeping proteins. Results obtained will provide a rational framework for subsequent studies, which form the secondary aims of the project. These are the clarification of the importance of the putative virulence determinant PauA, by exploring the presence/absence of pauA and diversity at the molecular level, and identification and characterisation of novel virulence determinants using representational difference analysis.

Summary

unavailable

Committee	Closed Committee - Animal Sciences (AS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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