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Molecular studies of the crustacean innate immune system. Do immunostimulants really protect against infection?
Reference
S15353
Principal Investigator / Supervisor
Dr Valerie Smith
Co-Investigators /
Co-Supervisors
Dr Christopher Hauton
Institution
University of St Andrews
Department
Biology
Funding type
Research
Value (£)
275,756
Status
Completed
Type
Research Grant
Start date
01/02/2002
End date
30/04/2005
Duration
39 months
Abstract
This project aims to ascertain whether or not substances claimed to enhance disease resistance in crustacean shellfish are actively effective in up-regulating the expression of immune genes and conferring protection on the host that is appropriate for use with juveniles over prolonged periods. Specifically, the work will test a range of commercial and non-commercial immunostimulants for their ability to up-regulate the expression of marker genes known to encode four immunologically important proteins in vitro and in vivo using real-time PCR techniques. The project will further investigate the efficacy of confirmed stimulants in enhancing the survival of post-larvae against pathogenic and opportunistic bacterial challenge.
Summary
unavailable
Committee
Closed Committee - Animal Sciences (AS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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