Award details

Molecular organisation and elasticity of fibrillin-rich tissues under physiological conditions

Reference	S15326
Principal Investigator / Supervisor	Professor Timothy Wess
Co-Investigators / Co-Supervisors
Institution	University of Stirling
Department	Biological and Environmental Sciences
Funding type	Research
Value (£)	155,320
Status	Completed
Type	Research Grant
Start date	01/10/2001
End date	31/08/2003
Duration	23 months

Abstract

The purpose of this proposal is to determine the contribution from different levels of molecular organisation in fibrillin rich tissues at which the characteristic viscoelastic biomechanical properties occur. This will use state-of-the-art X-ray diffraction techniques in conjunction with biomechanical measurements that allow the behaviour to be determined under physiological conditions. Fibrillin microfibrils are widely-distributed extracellular matrix assemblies that endow all dynamic connective tissues with long-range elastic recoil and form the template for tropoelastin in developing elastic fibres. This exciting and timely proposal is made possible by combing powerful complementary expertises and will reinforce and extend our successful collaboration.

Summary

unavailable

Committee	Closed Committee - Animal Sciences (AS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

Associated awards:

BBS/X/00042 Molecular organisation and elasticity of fribrillin-rich tissues under physiological conditions

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