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Putting the C. elegans genome to work: a proteome model for studying the establishment of chronic parasitic nematode infections
Reference
S14953
Principal Investigator / Supervisor
Professor Peter Brophy
Co-Investigators /
Co-Supervisors
Professor John Barrett
,
Dr Conor Caffrey
Institution
Aberystwyth University
Department
Inst of Biological, Environ & Rural Sci
Funding type
Research
Value (£)
231,512
Status
Completed
Type
Research Grant
Start date
01/04/2001
End date
30/11/2004
Duration
44 months
Abstract
Proteomics and the readily manipulated Heligmosomoides polygyrus nematode - mouse model are powerful tools to systematically identify for the first time the major gene products of relevance to the establishment of parasitic nematode chronic infections. By assigning a chronicity function to groups of proteins in our global learning models this integrated approach will identify new strategies and targets for future interruption of nematode infection and provide the research community with additional tools to investigate host-parasite interactions.
Summary
unavailable
Committee
Closed Committee - Animal Sciences (AS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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