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Functional genomics of ecdysteroid homeostasis in regulation of insect development
Reference
S14676
Principal Investigator / Supervisor
Professor Huw Rees
Co-Investigators /
Co-Supervisors
Dr Philip Turner
Institution
University of Liverpool
Department
Sch of Biological Sciences
Funding type
Research
Value (£)
201,192
Status
Completed
Type
Research Grant
Start date
01/03/2001
End date
01/03/2004
Duration
36 months
Abstract
Our studies on mechanisms involved in regulation of fluctuating ecdysteroid (moulting hormone) concentrations during insect development in a lepidopteran species have resulted in characterization of several enzymes and their cDNAs. The aims are to elucidate the functional significance of these enzymes, particularly catalysing interconversion of ecdysteroid and 3-dehydroecdysteroid, and of the individual ecdysteroids. This requires the ability to manipulate expression of the genes and to examine downstream effects of the ecdysteroids on global gene expression by complementary DNA array and proteomic approaches to Drosophila.
Summary
unavailable
Committee
Closed Committee - Animal Sciences (AS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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