Award details

Identification of novel targets of methyl farnesoate action in the regulation of crustacean reproductive development

Reference	S13882
Principal Investigator / Supervisor	Dr Geoffrey Wainwright
Co-Investigators / Co-Supervisors	Professor Huw Rees
Institution	University of Liverpool
Department	Sch of Biological Sciences
Funding type	Research
Value (£)	180,044
Status	Completed
Type	Research Grant
Start date	01/04/2001
End date	01/04/2004
Duration	36 months

Abstract

There is evidence that the isoprenoid hormone, methyl farnesoate (MF), is involved in regulation of ovarian maturation in crustaceans. However, the precise biochemical target(s) of MF action in stimulating ovarian maturation are unknown. The main objective of the project is to identify target proteins and mRNAs that are regulated by MF action on ovaries. The specific aims are: 1) to identify proteins and mRNAs that are differentially expressed in ovaries upon treatment with MF, using proteomic- and genomic-based methods; and 2) to determine expression profiles of MF-regulated proteins and mRNAs during ovarian development. The results will enhance understanding of the hormonal control of reproductive development in female crustaceans.

Summary

unavailable

Committee	Closed Committee - Animal Sciences (AS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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