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Clonal analysis of the CNS of Drosophila

ReferenceS13323
Principal Investigator / Supervisor Professor David Shepherd
Co-Investigators /
Co-Supervisors
Institution University of Southampton
DepartmentCentre for Biological Sciences
Funding typeResearch
Value (£) 177,112
StatusCompleted
TypeResearch Grant
Start date 01/10/2000
End date 30/09/2003
Duration36 months

Abstract

The aim of this project is to use the MARCM technique to analyse the entire process of neurogenesis in Drosophila from the first division of a neuroblast to the last. The project is in two sections. Section 1 proposes to make a complete analysis of neurogenesis in the thoracic neuromeres to describe their clonal organisation and identify the major anatomical and functional features of complete neuronal lineages. Section 2 uses mutations and ectopic gene expression to examine the roles of the engrailed and frazzled genes in controlling the development of identified clones of neurons.

Summary

unavailable
Committee Closed Committee - Animal Sciences (AS)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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