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Mechanisms of learning and memory in a model invertebrate system

Reference	S11606
Principal Investigator / Supervisor	Professor Paul Benjamin
Co-Investigators / Co-Supervisors	Professor Richard Andrew, Professor George Kemenes, Dr Sergei Korneev, Professor Michael O'Shea
Institution	University of Sussex
Department	Biology and Environmental Science
Funding type	Research
Value (£)	783,844
Status	Completed
Type	Research Grant
Start date	01/10/1999
End date	01/04/2003
Duration	42 months

Abstract

We propose a five-year interdisciplinary project to investigate the behavioural, cellular and molecular mechanisms of associative appetitive conditioning in the feeding system of the snail, Lymnaea stagnalis. The emphasis of the study is to treat learning as a property of the whole behavioural and neural system. We will investigate the distributed sites of plasticity, the function of known (NO- sGC, CREB) and novel genes and molecular pathways involved in learning and memory and the molecular and cellular mechanisms of learning, involving key molecules (NO, serotonin, neuropeptides), at the behavioural, whole circuit levels and in cell culture. The project will link to associated work on the computer modelling of learning and memory.

Summary

unavailable

Committee	Closed Committee - Animal Sciences (AS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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