BBSRC Portfolio Analyser
Award details
Cellular and molecular characterisation of ovine CD1 expression
Reference
S11255
Principal Investigator / Supervisor
Professor Susan Rhind
Co-Investigators /
Co-Supervisors
Professor John Hopkins
Institution
University of Edinburgh
Department
Veterinary Pathology
Funding type
Research
Value (£)
95,878
Status
Completed
Type
Research Grant
Start date
03/05/1999
End date
03/05/2001
Duration
24 months
Abstract
The CD1 family is a unique third lineage of antigen presenting molecules. Members of the CD1 family have been shown to play a key role in presentation of non-protein antigens to subsets of T lymphocytes. The aims of this project involve the unambiguous characterisation of a novel CD1 gene which is likely to represent the ovine homologue of human CD1E. In parallel, full molecular characterisation of the ovine CD1 family together with investigation of the expression of both proteins and transcripts will be carried out in a range of tissues. In view of the likely role of CD1 in innate and mucosal immunity, detailed expression studies will be carried out in intestinal and pulmonary tissue.
Summary
unavailable
Committee
Closed Committee - Animal Sciences (AS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
I accept the
terms and conditions of use
(opens in new window)
export PDF file
back to list
new search