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The neural basis of executive functions
Reference
S10196
Principal Investigator / Supervisor
Professor Philip Winn
Co-Investigators /
Co-Supervisors
Institution
University of St Andrews
Department
Biology
Funding type
Research
Value (£)
145,897
Status
Completed
Type
Research Grant
Start date
09/03/1999
End date
09/03/2002
Duration
36 months
Abstract
Executive functions include cognitive processes fundamental to the proper sequencing and planning of action. They are associated with the frontal cortex and the subcortial structure most intimately connected to it, the striatum. Recent research has shown deficits matching those produced by frontal damage following bilateral lesion of the pedunculopontine tegmental nucleus (PPTg), a structure relatively low in the brain that receives output from frontostriatal systems. The hypothesis is that the PPTg is an important output station for frontostriatal systems. The hypothesis is that the PPTg is an important output station for frontostriatal systems and contributes to executive functioning. The project will use tests of executive function to investigate the relationships between frontostriatal systems and the PPTg. The knowledge gained will increase basic understanding of how animals use highly processed cortical information to produce action.
Summary
unavailable
Committee
Closed Committee - Animal Sciences (AS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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