Award details

Proteomics: resolving the molecular dynamics of nematode drug resistance

Reference	S10062
Principal Investigator / Supervisor	Professor John Barrett
Co-Investigators / Co-Supervisors	Professor Peter Brophy
Institution	Aberystwyth University
Department	Inst of Biological, Environ & Rural Sci
Funding type	Research
Value (£)	152,008
Status	Completed
Type	Research Grant
Start date	01/02/1999
End date	01/02/2002
Duration	36 months

Abstract

Using avermectin susceptible and avermectin resistant strains of nematode the aim is to construct response maps of those proteins whose expression is altered by avermectin treatment. As well as giving an overall picture of the physiological basis of avermectin resistance the response maps will aid the identification of 1) proteins that might act as markers for the early, reversible stages of drug resistance 2) proteins that might be putative targets for the development of new drugs and 3) proteins which may be new targets for existing drugs.

Summary

unavailable

Committee	Closed Committee - Animal Sciences (AS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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