Award details

Intersegmental co-ordination of local circuits for the control of posture and locomotion

Reference	S09582
Principal Investigator / Supervisor	Professor Malcolm Burrows
Co-Investigators / Co-Supervisors	Professor Berthold Hedwig
Institution	University of Cambridge
Department	Zoology
Funding type	Research
Value (£)	192,921
Status	Completed
Type	Research Grant
Start date	01/10/1998
End date	01/04/2002
Duration	42 months

Abstract

Adaptive locomotion depends on co-ordinated movements of all of the limbs. Circuits of local neurones control the movements of an individual limb, so co-ordination must require a flow of information to these local circuits from the brain, and between the limbs. To understand these intersegmental control mechanisms we will focus on three interrelated questions, exploiting our detailed knowledge of the local circuits themselves. First, are the mechansensory neurones from limb receptors regulated presynaptically by signals from the brain and from other limbs? Second, what are the mechanisms and pathways by which individual neurones in the brain initiate, regulate and terminate a motor pattern? Third, how is spatial sensory information from one limb transformed into a temporal sequence of motor activity of another limb to produce an accurately targeted movement?

Summary

unavailable

Committee	Closed Committee - Animal Sciences (AS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

I accept the terms and conditions of use (opens in new window)

export PDF file

back to list new search