Award details

Presynaptic modulation of sensory signals

Reference	S08698
Principal Investigator / Supervisor	Professor Philip Newland
Co-Investigators / Co-Supervisors
Institution	University of Southampton
Department	Centre for Biological Sciences
Funding type	Research
Value (£)	172,775
Status	Completed
Type	Research Grant
Start date	01/04/1998
End date	31/05/2001
Duration	38 months

Abstract

Without regulation, the massive barrage of sensory inflow impinging on the brain would rapidly saturate its processing capabilities. One regulatory mechanism that matches sensory inflow to the specific needs of an animal is presynaptic inhibition of primary sensory neurones. Presynaptic inhibition can be generated through different mechanisms and I will analyse how the effects mediated by two of these inhibitory mechanisms interact on specific sensory neurones. I will take advantage of the benefits of an invertebrate, the crayfish, which include a detailed knowledge of its neuronal networks and the relatively large size of individual neurones, to analyse presynaptic inhibition using electrophysiological and pharmacological techniques.

Summary

unavailable

Committee	Closed Committee - Animal Sciences (AS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

I accept the terms and conditions of use (opens in new window)

export PDF file

back to list new search