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Avian rhinotracheitis virus (ARTV): identification of protection-inducing proteins and mechanisms of variation within them

Reference	S08057
Principal Investigator / Supervisor	Professor David Cavanagh
Co-Investigators / Co-Supervisors
Institution	The Pirbright Institute
Department	Div of Molecular Biology
Funding type	Research
Value (£)	58,960
Status	Completed
Type	Research Grant
Start date	15/02/1997
End date	15/02/2000
Duration	36 months

Abstract

The aims are to assess (a) the extent to which the fusion (F) and G glycoproteins of ARTV induce cross-protective immunity in poultry; (b) the extent and mechanisms by which these proteins change and (c) to follow changes in the relative proportions of subtype A and B ARTV in the national flock. The ARTV genes will be expressed using fowl pox virus recombinants. Cross-protection experiments will be performed using turkey poults. Protein sequence variation will be assessed by gene sequencing and monoclonal antibody analysis.

Summary

unavailable

Committee	Closed Committee - Animal Sciences (AS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	LINK: Animal Sciences Committee (ASL) [1996-2004]
Funding Scheme	X – not Funded via a specific Funding Scheme

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