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Physiological and ultrastructural study of the performance of synapses which transmit graded potentials
Reference
S06923
Principal Investigator / Supervisor
Dr Peter Simmons
Co-Investigators /
Co-Supervisors
Institution
Newcastle University
Department
Institute of Neuroscience
Funding type
Research
Value (£)
135,706
Status
Completed
Type
Research Grant
Start date
01/05/1997
End date
01/05/2000
Duration
36 months
Abstract
The most significant aim is to determine the resolution with which graded potentials are conveyed across synapses made by neurones that operate without trains of all-or-none impulses. The techniques will be to measure the linked neurones in the locust ocellar visual system. Mechanisms that limit synaptic resolution will be sought, including the quantal nature of transmitter release. Ultrastructural study will be undertaken to determine how vesicles are mobilised and recycled at the different discrete synapses that constitute a single functional synaptic connection.
Summary
unavailable
Committee
Closed Committee - Animal Sciences (AS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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