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A novel role for the intestine in acid-base regulation of marine teleosts
Reference
S06849
Principal Investigator / Supervisor
Professor Rod Wilson
Co-Investigators /
Co-Supervisors
Institution
University of Exeter
Department
Biosciences
Funding type
Research
Value (£)
118,452
Status
Completed
Type
Research Grant
Start date
01/12/1996
End date
01/04/1999
Duration
28 months
Abstract
The applicant has recently discovered that seawater trout excrete alkaline fluid via the intestine (pH 8.9, [HCO3- + CO32-] content = 156 mEqkg-1; Wilson et al., 1996 submitted). This work has highlighted a significant and previously unrecognised role for the gut in acid- base balance of marine teleost fish and calls into question conventional theory regarding the dominant role of the gills and kidney in acid-base regulation of fishes. This project will use seawater-acclimated rainbow trout to i) quantify the significance of intestinal base excretion relative to the acid-base functions of the gills, kidney and skin, ii) determine whether intestinal base secretion is responsive to extracellular acid-base status and, if so, to investigate the possible forms of regulation (eg hormonal), and iii) investigate the sites and mechanisms of base secretion within the intestine and whether it is dependent on or independent of the osmoregulatory functions of the gut.
Summary
unavailable
Committee
Closed Committee - Animal Sciences (AS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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