Award details

Mandibular organ-inhibiting hormone and methyl farnesoate in control of moulting and reproduction in crabs

Reference	S03980
Principal Investigator / Supervisor	Professor Huw Rees
Co-Investigators / Co-Supervisors	Dr Philip Turner, Professor Simon Webster
Institution	University of Liverpool
Department	Sch of Biological Sciences
Funding type	Research
Value (£)	221,434
Status	Completed
Type	Research Grant
Start date	01/09/1995
End date	10/04/1999
Duration	44 months

Abstract

The juvenoid, methyl farnesoate (MF), secreted by the mandibular organs (MO) appears to be involved in control of moulting and reproduction in crustaceans, together with the peptide hormones, vitellogenesis- and moult-inhibiting hormones. We have discovered that control of MF synthesis is by a new neuropeptide, mandibular organ-inhibiting hormone (MO-IH), opening up a novel set of interendocrine interactions requiring elucidation to redefine models of endocrine regulation. Using molecular biological, immunocytochemical and bioassay techniques, this project will (1) investigate the physiological role of MO-IH, MF and ecdysteroids in moulting and reproduction, (2) isolate the cDNA encoding MO-IH, (3) study the temporal expression of MO-IH at both RNA and protein levels, and (4) investigate the MO-IH neurosecretory pathway. This information will provide a basis for ultimate utilisation in the aquaculture industry.

Summary

unavailable

Committee	Closed Committee - Animal Sciences (AS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

I accept the terms and conditions of use (opens in new window)

export PDF file

back to list new search