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The response to immunological stress in nematodes
Reference
S03787
Principal Investigator / Supervisor
Professor David Idris Pritchard
Co-Investigators /
Co-Supervisors
Dr David De Pomerai
Institution
University of Nottingham
Department
Sch of Biosciences
Funding type
Research
Value (£)
47,084
Status
Completed
Type
Research Grant
Start date
01/04/1995
End date
01/04/1998
Duration
36 months
Abstract
The nematode cuticle is undoubtedly antigenic, and reputed to be vulnerable to immune attack. However, its vulnerability has never been fully tested experimentally. We therefore propose to use a stress-inducible transgenic strain of C. elegans in a pilot study to assess quantitatively the effect of immunological stress on nematode physiology. Our experiments will heighten our understanding of nematode defences against immunological attack. In the longer term, this system will allow us to identify key components of the host and parasite defence pathways.
Summary
unavailable
Committee
Closed Committee - Animal Sciences (AS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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