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Targeted cell ablation to study the role of cell-cell interaction in axon guidance

ReferenceS02193
Principal Investigator / Supervisor Professor Andrea Brand
Co-Investigators /
Co-Supervisors
Institution University of Cambridge
DepartmentGurdon Institute
Funding typeResearch
Value (£) 156,986
StatusCompleted
TypeResearch Grant
Start date 05/02/1995
End date 05/02/1998
Duration36 months

Abstract

Screen for transgenic lines that express GAL4 in the ventral midline cells of the Drosophila embryonic central nervous system. Use these lines to drive expression of a GAL4-responsive toxin gene to specifically ablate midline cells. Characterise defects in axon guidance resulting from the ablation of specific cells.

Summary

unavailable
Committee Closed Committee - Animal Sciences (AS)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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