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Regulation of carbon allocation through the pathway of fatty acid synthesis

ReferenceRSP07836
Principal Investigator / Supervisor Dr Matthew Hills
Co-Investigators /
Co-Supervisors
Dr Stephen Rawsthorne
Institution John Innes Centre
DepartmentJohn Innes Centre Department
Funding typeResearch
Value (£) 188,367
StatusCompleted
TypeResearch Grant
Start date 11/03/1997
End date 11/03/2000
Duration36 months

Abstract

We will investigate the regulation of fatty acid synthesis in isolated intact plastids from developing seeds and leaves of oilseed rape. We will study the effect of acyl-CoA/acyl-CoA binding protein (ACBP) on the kinetics of transporters and enzymes of the pathway of fatty acid synthesis and on the concentrations of metabolic intermediates to determine at which points regulation of fatty acid synthesis by its product is occurring. We will also study the role of ACBP taking an in vivo approach by expressing sense and antisense constructs for ACBP in transgenic oilseed rape plants, and study the effects of these constructs on lipid metabolism.

Summary

unavailable
Committee Closed Committee - Plant & Microbial Sciences (PMS)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative Resource Allocation and Stress in Plants (RSP) [1995]
Funding SchemeX – not Funded via a specific Funding Scheme
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