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Glyoxylate cycle function and resource allocation during adaptation to environmentally-induced carbohydrate limitation

ReferenceRSP07677
Principal Investigator / Supervisor Dr S Smith
Co-Investigators /
Co-Supervisors
Dr James Bryce
Institution University of Edinburgh
DepartmentInst of Cell and Molecular Biology
Funding typeResearch
Value (£) 132,466
StatusCompleted
TypeResearch Grant
Start date 21/07/1997
End date 31/08/2000
Duration39 months

Abstract

Carbohydrate deprivation of cells or tissues is common in plants. Other carbon sources may then be employed for respiration or biosynthesis. Glyoxylate cycle enzymes are synthesised in response to carbohydrate deprivation, but their function is unknown. The cycle could have respiratory, anapleurotic or gluconeogenic roles, with importance in resource allocation in growing plants and harvested products. The aims are (1) to determine if the cycle provides mechanism to adapt to and survive carbohydrate deprivation, and (2) to elucidate the metabolic role of the cycle during carbohydrate deprivation. Arabidopsis insertion mutants for glyoxylate cycle enzymes will be isolated, mutant phenotypes analysed, and specific radioactive substrates used to trace glyoxylate cycle products.

Summary

unavailable
Committee Closed Committee - Plant & Microbial Sciences (PMS)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative Resource Allocation and Stress in Plants (RSP) [1995]
Funding SchemeX – not Funded via a specific Funding Scheme
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