Award details

Confocal laser scanning microscope

Reference	REI20554
Principal Investigator / Supervisor	Professor Stephen Goodwin
Co-Investigators / Co-Supervisors	Professor Shireen Davies, Professor Julian Dow, Professor Darren Monckton, Dr Kevin O'Dell
Institution	University of Glasgow
Department	Molecular Genetics
Funding type	Research
Value (£)	106,943
Status	Completed
Type	Research Grant
Start date	01/12/2003
End date	31/05/2004
Duration	6 months

Abstract

We propose to purchase a confocal laser scanning microscope system from the Bio-Rad Ltd to serve, as a central confocal for all our divisional microscopuy needs. The applicants have outlined several major areas of study that will directly benefit from sustained access to a confocal microscope, these are: Neuroanatomical analysis of fruitless-expressing neurons involved in male sexual behaviour in Drosophila melanogaster (Dr Goodwin). Drosophila integrative physiology group (Prof Dow and Dr Davies). Molecular pathways in myotonic dystrophy (Dr Monckton). Drosophila as a model of Human Genetic Disease (Drs O Dell and Monckton). The Manifestation of Female Sex-Specific Behaviours in Drosophila melanogaster (Drs O Dell and Goodwin). There are additional projects within the division of Molecular Genetics that will also benefit from fluroescence confocal image analysis. These include: i) Co-localisation of nuclear aggegrates and DNA repair activity in Huntingdons disease neurons (Dr Peggy Shelbourne). ii) Subcellular targeting of mutant MECP2 in patients with Rett syndrome (Dr Mark Bailey). iii) Analysis of cellular gene expression patterns in the tissues of Epstein Barr viral transgenic mice (Dr Joanna Wilson).

Summary

unavailable

Committee	Closed Committee - Genes & Developmental Biology (GDB)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	Research Equipment Initiative 2003 (RE2) [2003]
Funding Scheme	X – not Funded via a specific Funding Scheme

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