Award details

Ultracentrifugation facility for structural molecular and cellular biology and virology

Reference	REI18456
Principal Investigator / Supervisor	Professor Bernadette Byrne
Co-Investigators / Co-Supervisors	Professor Martin Buck, Dr Robert Coutts, Professor Paul Freemont, Professor So Iwata, Professor Thierry Soldati
Institution	Imperial College London
Department	Biological Sciences
Funding type	Research
Value (£)	193,748
Status	Completed
Type	Research Grant
Start date	01/04/2003
End date	01/04/2004
Duration	12 months

Abstract

Ultracentrifugation forms an essential part of many research laboratories. Within the Department of Biological Sciences at the South Kensington campus of Imperial College we have over 20 groups, divided between two buildings (Wolfson and Sir Alexander Fleming), which regularly make use of this technique. The current complement of ultracentrifuges and associated rotors are more than 15 years old and nearing the end of their useful life. In order to maintain the research within the department at an internationally competitive level we need to replace this equipment. The modern ultracentrifuges, combing faster speed with low vibration giving superior separation in a shorter running time, will both support present requirements and improve current protocols. Within this application we detail how several groups make use of ultracentifrugation as a tool and specify both the centrifuges and rotors which are a requirement of their research. The needs range from purification of viruses to protein sample clarification prior to crystallisation trial set-up. The centrifuges are essential to the research of these groups but will form a core facility which can be accessed by all the members of the department. This application requests funding for new ultracentrifuges and associated rotors, to equip both buildings.

Summary

unavailable

Committee	Closed Committee - Biomolecular Sciences (BMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	Research Equipment Initiative 2002 (REI) [2002]
Funding Scheme	X – not Funded via a specific Funding Scheme

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