Award details

Application of microwave technology in chemical biology

Reference	REI18434
Principal Investigator / Supervisor	Professor Sabine Flitsch
Co-Investigators / Co-Supervisors	Professor Michael Greaney, Professor Andrew Harrison, Professor Juan Mareque-Rivas, Professor Neil Robertson, Professor Nicholas Turner, Dr A Whittaker
Institution	University of Edinburgh
Department	Sch of Chemistry
Funding type	Research
Value (£)	31,404
Status	Completed
Type	Research Grant
Start date	30/04/2003
End date	30/11/2003
Duration	7 months

Abstract

The aim of the proposal is to apply recent advances in microwave technology to accelerate and enhance a wide range of projects at Edinburgh in organic synthesis, chemical biology and solid-state inorganic chemistry. In general, reactions conducted under microwave conditions proceed considerably faster than their counterparts under conventional conditions. Traditional heating techniques for organic systems (e.g. oil baths, sand baths, heating jackets) are typically slow and can generate temperature gradients within the sample. In addition, local overheating can lead to product, substrate and reagent decomposition. By contrast, in microwave dielectric heating the energy is introduced into the reaction vessel remotely, heating only the reactants and solvents, not the vessel itself. Moreover, in pressurised systems it is possible to rapidly increase the temperature far above the conventional boiling point of the solvent used. There is currently no such instrument available in the department and the present applications presents an exciting opportunity for the department to develop in collaboration with CEM a strong facility in the department that will benefit a range of research projects funded by the BBSRC and other bodies. The equipment will integrate well into a state-of-the-art parallel synthesis facility and excellent analytical departments.

Summary

unavailable

Committee	Closed Committee - Biomolecular Sciences (BMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	Research Equipment Initiative 2002 (REI) [2002]
Funding Scheme	X – not Funded via a specific Funding Scheme

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