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Population genomic and evolutionary biology of complex systems

Reference	REI18431
Principal Investigator / Supervisor	Professor Mark Blaxter
Co-Investigators / Co-Supervisors	Dr Peter Andolfatto, Professor Brian Charlesworth, Professor Deborah Charlesworth, Mr C Earl, Professor Peter Keightley, Professor Richard Michael Maizels, Professor Austin Smith
Institution	University of Edinburgh
Department	Inst of Evolutionary Biology
Funding type	Research
Value (£)	157,076
Status	Completed
Type	Research Grant
Start date	01/04/2003
End date	01/04/2008
Duration	60 months

Abstract

We would like to upgrade our very successful BBSRC-funded automated genetic analyser from its current gel-based instruments to a state of the art capillary instrument. The increased throughput and versatility of the chosen instrument, the ABI 3730, will facilitate many research programs funded by the BBSRC including: understanding the determinants of patterns of molecular evolution and the evolution of genomes, with particular reference to the effect of breeding systems and sex chromosomes on mutation patterns; the population and quantitative genetics of neutral and selected variation in wild and model populations with an emphasis on understanding the interplay between population history, current fitness and interactions between species and environments; the use of sequence data to reveal the biology of parasitism, in developing robust phylogenies for parasites and other metazoans and in estimating diversity within phyla and within species; supporting genomics-based programs investigating developmental mechanisms in stem cells and the evolution of pattern formation.

Summary

unavailable

Committee	Closed Committee - Genes & Developmental Biology (GDB)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	Research Equipment Initiative 2002 (REI) [2002]
Funding Scheme	X – not Funded via a specific Funding Scheme

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