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Salt-induced genes in the sigma M regulon of Bacillus subtilis
Reference
PRS12203
Principal Investigator / Supervisor
Professor Anne Moir
Co-Investigators /
Co-Supervisors
Institution
University of Sheffield
Department
Molecular Biology and Biotechnology
Funding type
Research
Value (£)
176,296
Status
Completed
Type
Research Grant
Start date
01/04/2000
End date
01/04/2003
Duration
36 months
Abstract
Sigma M is newly identified sigma factor in B. subtilis: strains lacking this sigma factor are sensitive to salt stress in early growth phase. The project aims (1) to identify the components of the sigma M regulon, and to characterise the transcriptional regulation of salt-regulated genes and (2) to explore the regulation of sigma M activity and expression, including the environmental signals responsible for activation and for switching off of activity. The results will clarify the role of the sigma factor in continued growth from low cell density in a medium of high salt concentration
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
Prokaryotic Responses to Environmental Stress (PRS) [1999]
Funding Scheme
X – not Funded via a specific Funding Scheme
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