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Towards a molecular understanding of gene-to-gene specificity in fungal pathogenesis of Arabidopsis and Brassica

Reference	PMB00552
Principal Investigator / Supervisor	Professor James Beynon
Co-Investigators / Co-Supervisors	Professor Ian Crute, Professor Eric Holub
Institution	Imperial College London
Department	Biological Sciences
Funding type	Research
Value (£)	231,661
Status	Completed
Type	Research Grant
Start date	07/12/1992
End date	06/09/1997
Duration	57 months

Abstract

We seek an understanding of gene-for-gene specificity by using two biotrophic pathogens of crucifers: Peronspora parasitica (Pp) and Albugo candida (Ac) as models. From the analysis of one cross (from which 300 recombinant inbred lines are being produced) we will clone three previously identified alleles from Arabidopsis thaliana (At) for resistance to Pp (RPp alleles). Each allele conditions a characteristic and different pathogen response phenotype. To assist in this work, we will select Pp isolates which allow the unambiguous detection of individual RPp alleles and identify mutants with altered pathogen response phenotypes. Additionally, we will map and clone loci in At controlling response to Ac and characterise and map loci in Brassica spp. for resistance to Pp and Ac. (Joint with grant PMB00578).

Summary

unavailable

Committee	Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	Plant Molecular Biology II (PM2) [1986]
Funding Scheme	X – not Funded via a specific Funding Scheme

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