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Towards cloning the gene that controls chromosome pairing and stabilises the polyploid genome of Brassica napus

Reference	PAG04446
Principal Investigator / Supervisor	Dr Martin Trick
Co-Investigators / Co-Supervisors	Professor John Parker
Institution	John Innes Centre
Department	John Innes Centre Department
Funding type	Research
Value (£)	78,139
Status	Completed
Type	Research Grant
Start date	04/03/1996
End date	04/03/1999
Duration	36 months

Abstract

Over 50% of plant species, including major crops, are polypoids. Polypoid species control chromosome pairing at meiosis, so that only truly homoeologous chromosomes, and not related homeologues, pair and recombine. In tetraploid Brassica napus, allelic variation at a single locus determines whether chromosomes form bivalent pairs (with homologues) or multivalent associations (with homoeologues). This gene will be mapped in B. napus and isolated via positional cloning with shuttling between the collinear genomes of Brassica and Arabidopsis. The biochemistry and cell biology of the gene product will provide a valuable insight into a process which is vital to meiosis and sexual reproduction.

Summary

unavailable

Committee	Closed Committee - Genes & Developmental Biology (GDB)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	Plant & Animal Genome Analysis (PAG) [1993-1995]
Funding Scheme	X – not Funded via a specific Funding Scheme

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