Award details

Exploitation of visible and promiscuous homologous recombination as a key to genome analysis in grasses

Reference	PAG04444
Principal Investigator / Supervisor	Dr Michael Hayward
Co-Investigators / Co-Supervisors	Dr J Forster, Dr Huw Thomas
Institution	Inst of Grassland and Environmental Res
Department	Cell Biology Department
Funding type	Research
Value (£)	183,489
Status	Completed
Type	Research Grant
Start date	01/11/1995
End date	01/11/1998
Duration	36 months

Abstract

Recombination occurs freely between homoeologous chromosomes of Lolium perenne and Festuca pratensis and the genomes are substantially collinear. Nevertheless, the chromosomes can be distinguished by GISH. The fate of single Festuca-derived chromosome arms in a Lolium background will be monitored cytologically and genetically in the presence and absence of the Lolium pairing control gene. The gene will be tagged with a molecular marker, ultimately allowing the molecular study of its mode of action. The physical and genetic maps will be correlated and the influence of the pairing gene seen. The data will be of fundamental importance in understanding the control of homoeologous recombination with relevance to other species.

Summary

unavailable

Committee	Closed Committee - Genes & Developmental Biology (GDB)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	Plant & Animal Genome Analysis (PAG) [1993-1995]
Funding Scheme	X – not Funded via a specific Funding Scheme

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