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Surface plasmon resonance equipment to study engineered proteins and synthetic peptides that bind to IgG-Fc and IgE-Fc
Reference
PAC02694
Principal Investigator / Supervisor
Professor Brian Sutton
Co-Investigators /
Co-Supervisors
Institution
King's College London
Department
GKT School of Biomedical Sciences
Funding type
Research
Value (£)
62,000
Status
Completed
Type
Research Grant
Start date
01/12/1994
End date
01/12/1997
Duration
36 months
Abstract
i) monitor the IgG-binding properties of modified bacterial proteins A, G and L to facilitate the development of improved preparative reagents for biotechnology and clinical science; ii) monitor inhibition of IgE-receptor binding by synthetic peptides to develop blocking agents for allergy. iii) develop the use of SPR to study ligand binding to membrane-bound proteins. Projects to run concurrently, and lead compounds of potential interest to industry expected within two years.
Summary
unavailable
Committee
Closed Committee - Biomolecular Sciences (BMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
Pharmaceuticals/Chemicals - ROPA (PAC) [1994]
Funding Scheme
X – not Funded via a specific Funding Scheme
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