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Functional analysis of the glucosylation of auxin abscisic acid and their metabolites in Arabidopsis thaliana
Reference
P20194
Principal Investigator / Supervisor
Professor Dianna Bowles
Co-Investigators /
Co-Supervisors
Dr Eng-Kiat Lim
,
Dr Joe Ross
Institution
University of York
Department
Biology
Funding type
Research
Value (£)
290,689
Status
Completed
Type
Research Grant
Start date
01/04/2004
End date
29/02/2008
Duration
47 months
Abstract
Six UDP-glucosyltransferases (UGTs) of Arabidopsis have been identified that recognise auxins and abscisic acid (ABA). Surprisingly, five of the UGTs glucosylate both hormones and one, 71B6, recognises only ABA, preferring the naturally occurring (+)-ABA. To understand the relevance of these data, we need to define where and when each UGT is expressed and the phenotypic consequences of changing that expression. We have knock-outs already for 4 of the 6 genes, including 71B6; an RNAi strategy for the silencing individual or clusters of UGTs has also been optimised. Through target profiling we will link UGT expressions to metabolite profiles of each hormone and start to determine the influence of glycosylation on these profiles and on the plants hormone metabolism.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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