BBSRC Portfolio Analyser
Award details
The mechanism of action of SFR2 protein in enabling plant cells to tolerate freezing
Reference
P19249
Principal Investigator / Supervisor
Professor Peter Bramley
Co-Investigators /
Co-Supervisors
Dr Glenn Thorlby
Institution
Royal Holloway, Univ of London
Department
Biological Sciences
Funding type
Research
Value (£)
222,448
Status
Completed
Type
Research Grant
Start date
01/05/2003
End date
30/04/2006
Duration
36 months
Abstract
The recently-identified SFR2 protein is a uniquely divergent beta-glycosidase. Nothing in previous knowledge indicates why or how such an enzyme should be essential for freezing tolerance (as, on genetic evidence, we know SFR2 to be). Thus the function of SFR2 in freezing tolerance is entirely novel. This proposal is for research to elucidate that function, by investigation of: (i) protein-intrinsic properties; the subcellular localisation and post-translational modification of SFR2 protein; (ii) substrate-specificity: the identity of SFR2 proteins target glycoside(s); (iii) the functionality of SFR2 homologues from freezing-sensitive species; and (iv) the spatial and temporal limits of SFR2s freezing-tolerance function.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
I accept the
terms and conditions of use
(opens in new window)
export PDF file
back to list
new search