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The role of cyclic ADP ribose in the circadian signalling network
Reference
P19207
Principal Investigator / Supervisor
Professor Alex Webb
Co-Investigators /
Co-Supervisors
Professor Dale Sanders
Institution
University of Cambridge
Department
Plant Sciences
Funding type
Research
Value (£)
231,768
Status
Completed
Type
Research Grant
Start date
16/10/2003
End date
15/10/2006
Duration
36 months
Abstract
Important new data strongly suggests that cyclic ADP ribose (cADPR) is a component of the signalling pathway by which the circadian clock regulates cellular events. We will test the hypothesis that oscillations in cADPR are an output of the circadian clock that mediate circadian oscillations in cytosolic free calcium in Arabidopsis. We will combine imaging, pharmacology, biochemistry, cell physiology, reverse genetics and mutant analysis to test this hypothesis.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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