Award details

Characterisation of biofilm development in Rhodobacter sphaeroides

Reference	P18634
Principal Investigator / Supervisor	Dr Helen Packer
Co-Investigators / Co-Supervisors	Professor Judith Armitage
Institution	Oxford Brookes University
Department	Faculty of Health and Life Sciences
Funding type	Research
Value (£)	174,032
Status	Completed
Type	Research Grant
Start date	14/07/2003
End date	13/07/2006
Duration	36 months

Abstract

Biofilm development will be quantified in Rhodobacter sphaeroides WS8 under a range of different environmental conditions using GFP as a marker and reporter. Confocal and fluorescence microscopy will be used to quantify development. The roles of motility, the chemotaxis (che) system and the quorum sensing (cer) system in biofilm development, maintenance and dispersal in R. sphaeroides will be determined using mutational studies. Genes involved in biofilm development will be detected using in vivo promoter trapping technology (RIVET) and these will be characterised. Six of these genes will be studied further in vivo, using mutational studies and GFP tagging, to elucidate their role in biofilm formation and development

Summary

unavailable

Committee	Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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