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RNAi as a basis for defining both nematode and plant genes involved in compatiblity and to provide novel control

Reference	P18264
Principal Investigator / Supervisor	Prof. Howard Atkinson
Co-Investigators / Co-Supervisors	Professor Peter Urwin
Institution	University of Leeds
Department	Plant Biochemistry & Biotechnology
Funding type	Research
Value (£)	240,768
Status	Completed
Type	Research Grant
Start date	01/05/2003
End date	30/04/2006
Duration	36 months

Abstract

We have achieved RNA interference (RNAi) for non-feeding infective cyst-nematodes. It provides a powerful basis for functional genomics to define gene expression essential to a plant- pathogen interaction. The approach will define this sub-set from among the growing catalogue of host and nematode genes that show changes in expression at that time. The consequences of perturbing individual genes by RNAi will be monitored using a range of progress markers including reporter plants. The work will: 1) define cyst nematode genes essential for plant parasitism by females; 2) determine if RNAi of these genes directed from the plant is a basis for control; 3) use RNAi to identify those plant genes that are essential to the susceptible host response.

Summary

unavailable

Committee	Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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