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Characterising determinants of infection-related development in Magnaporthe grisea using proteomic analysis
Reference
P18247
Principal Investigator / Supervisor
Professor Nicholas Talbot
Co-Investigators /
Co-Supervisors
Institution
University of Exeter
Department
Biosciences
Funding type
Research
Value (£)
213,324
Status
Completed
Type
Research Grant
Start date
01/10/2003
End date
30/09/2006
Duration
36 months
Abstract
The project will use proteomic analysis to investigate infection- related development by the rice blast fungus Magnaporthe grisea. The full genome sequence of this phytopathogenic fungus will shortly become available and the project will utilise the BBSRC- funded resource centre for proteomics of microbial eukaryotes at Aberdeen. Major landmarks in the M. grisea proteome will be identified and characterised and the magnitude of proteome changes during infection-related development will be assessed. The component of the proteome that is regulated by the PMK1 and MPS1 MAP kinase pathways, which regulate virulence-associated functions of diverse phytopathogenic fungi, will be identified. A sub-set of proteins identified in the project will be utilised to identify corresponding genes which will be investigated via targeted disruption.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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