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Biochemical characterisation of SYMRK a novel receptor-like kinase required for early signal transduction in root symbioses
Reference
P18240
Principal Investigator / Supervisor
Professor Jonathan Jones
Co-Investigators /
Co-Supervisors
Institution
University of East Anglia
Department
Sainsbury Laboratory
Funding type
Research
Value (£)
215,688
Status
Completed
Type
Research Grant
Start date
01/09/2002
End date
01/09/2005
Duration
36 months
Abstract
A novel receptor-like kinase SYMRK (for symbiosis receptor-like kinase) from the legume Lotus japonicus is required for the earliest steps in symbiotic signal transduction. SYMRK plays a role in a signalling pathway between the perception of microbial signal compounds and the induction of calcium-spiking and symbiosis- activated gene expression. SYMRK is predicted to have a signal peptide, an extracellular domain comprising leucine-rich repeats, a transmembrane and an intracellular protein kinase domain. This proposal is to characterise the SYMRK protein at the biochemical level and to isolate interacting proteins in order to unravel the symbiotic signal transduction pathway leading to the development of root symbioses.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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