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The relative roles of cinnamyl alcohol dehydrogenase and sinapyl alcohol dehydrogenase in monolignol synthesis

Reference	P18182
Principal Investigator / Supervisor	Professor Claire Halpin
Co-Investigators / Co-Supervisors
Institution	University of Dundee
Department	College of Life Sciences
Funding type	Research
Value (£)	230,212
Status	Completed
Type	Research Grant
Start date	16/02/2003
End date	15/07/2006
Duration	41 months

Abstract

Circumstantial evidence suggests that a new lignin pathway enzyme, sinapyl alcohol dehydrogenase (SAD), is responsible for the conversion of sinapaldehyde to sinapyl alcohol in angiosperms. This conflicts with our own work on transgenic plants where antisense inhibition of a distinct enzyme, cinnamyl alcohol dehydrogenase (CAD), leads to accumulation of sinapaldehyde in lignin, supporting the conventional lignin pathway scheme where CAD catalyses sinapaldehyde reduction. The current application aims to clarify the roles of SAD and CAD in lignin biosynthesis by (a) suppressing SAD in transgenic plants and assessing the resulting changes to lignin and by (b) re-characterising existing CAD-suppressed plants in the light of the new data on SAD.

Summary

unavailable

Committee	Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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